PATH Biobank contains breast cancer specimens from more than 11,000 patients. All molecular subtypes are available. All samples are fresh-frozen and stored in the gas phase of liquid nitrogen.
- Tumor tissue, with an edge length of at least 3mm
- Normal tumor adjacent tissue correspondong to the tumor with an edge length of at least 3mm
- Blood serum, 1ml volume
The molecular subtypes were determined according to St. Gallen International Expert Consensus, using tumor grading as surrogate marker for Ki-67 expression. Only primary breast cancer cases without neoadjuvant therapy were included in the analysis of the molecular subtypes.